What Is the Function of the Release Factor Rf

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It has been reported to have multiple effects on the hypothalamo-pituitary-thyroid axis and the functioning of the thyroid gland. Nuclear factor erythroid 2-related factor 2 NRF2 also known as nuclear factor erythroid-derived 2-like 2 is a transcription factor that in humans is encoded by the NFE2L2 gene.


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Alderson RF et al.

. Truncated TrkB mediates the endocytosis and release of BDNF and neurotrophin-45 by rat astrocytes and schwann cells in vitro. Alcohol is one of the commonest illicit psychoactive substances consumed globally and is the worlds third largest risk factor for disease and disability. The encoded protein is involved in many cellular processes including cell differentiation cell growth apoptosis immune responses response to DNA damage and chromatin remodeling.

The protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. NRF2 is a basic leucine zipper bZIP protein that may regulate the expression of antioxidant proteins that protect against oxidative damage triggered by injury and inflammation according to preliminary. Post-translational modifications such as phosphorylation.

It has been reported to cause direct suppression of thyroid function by cellular toxicity and indirect. BDNF-triggered events in the rat hippocampus are required for both short- and long-term memory formation. Google Scholar Alonso M et al.


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